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. Author manuscript; available in PMC: 2016 Apr 12.
Published in final edited form as: Mol Pharm. 2015 Feb 25;12(4):1289–1298. doi: 10.1021/mp500847s

Figure 4.

Figure 4

Effect of GDC-0449 and miR-let7b on cell viability in human pancreatic cancer cell line by micelles. (A) HPAF-II, (B) Capan-1, (C) T3M4 and (D) MIA PaCa-2 cells (5000/well) were treated with micelles containing (blue bars) GDC-0449 (0, 1, 5, and 10 μM), (green bars) GDC-0449 and scrambled miRNA, (red bars) GDC-0449 and miR-let7b (10 pmol), (peach bars) miR-let7b alone, and (purple bars) blank for 48 h. Cell viability was measured by MTT assay at the end of incubation period. Data represent the mean ± SD (n = 3).