Immunostaining of cryosections for CD31 as a marker for microvessel density. GE11-linked mixed micelle-treated tumor section showed significant reduction of microvessel densities. Saline, HW12-linked mixed micelles, free GEM, unmodified micelles, and GE11-linked mixed micelle-treated tumor samples were cryosectioned, fixed, and immunostained with rat antimouse CD31 antibody (green) and DAPI-stained nuclei (blue). Scale bar, 100 μM.