Table 1.
Normal (n=7) |
RAS (n=7) |
ARAS (n=7) |
|
---|---|---|---|
Body weight, kg | 48.2±1.2 | 48.7±4.1 | 52.1±2.2 |
Degree of renal artery stenosis, % | 0 | 76.0±7.2* | 68.9±8.0* |
MAP, mmHg | 98.4±1.6 | 117.5±10.7* | 127.4±10.9* |
Total Cholesterol, mg/dl | 82.3±3.6 | 88.2±7.9 | 405.3±59.7*# |
LDL, mg/dl | 31.1±2.7 | 38.5±1.8 | 248.4±42.9*# |
Creatinine, mg/dl | 1.20±0.13 | 1.68±0.11* | 1.73±0.03* |
Plasma renin activity, ng/mL/h | 0.11±0.03 | 0.20±0.08 | 0.16±0.03 |
STK RBF, min/min | 640.0±45.1 | 405.5±90.0* | 436.7±67.7* |
STK GFR, ml/min | 87.9±7.8 | 60.6±6.4* | 59.6±5.0* |
MAP, mean arterial pressure; LDL, low density lipoprotein; RBF, renal blood flow; GFR, glomerular filtration rate; STK, stenotic kidney.
P<0.05 vs. Normal;
P<0.05 vs. RAS.