Table 1.
Case | Author | Year | Age (m) |
Gender | Breast Fed |
Bloody Stool |
Ganciclovir | Outcome / Complications |
---|---|---|---|---|---|---|---|---|
1 | Huang [1] | 1996 | 1.5 | F | No | No | No | Ileal perforation |
2 | Jonkhoff [2] | 1997 | 1.5 | M | No | Yes | No | Recovered without therapy |
3 | Quiros-Tejeira [3] | 1999 | 2 | M | Yes | No | Yes | 2 weeks GCV, Recovered |
4 | Fox [4] | 1999 | 1 | M | Yes | Yes | Yes | 4 weeks GCV, recovered. |
5 | Shinawi [5] | 2001 | 14 | M | No | NA | No | Recovered without GCV therapy |
6 | Iwanaga [6] | 2003 | 2 | F | Yes | No | Yes | 2 weeks GCV, Recovered |
7 | Rongkavilit [7] | 2004 | 2 | M | Yes | No | Yes | 3 weeks GCV, Recovered |
8 | Hinds [8] | 2004 | 2 | M | Yes | Yes | No | 3 weeks TPN, Recovered without GCV |
9 | Shimizu [9] | 2005 | 12 | M | Yes | No | No | Prolonged TPN with pancreatitis and pseudocyst. Recovered without GCV |
10 | Buonomo [10] | 2006 | 7 | M | Yes | Yes | Yes | 5 weeks VGC, Recovered |
11 | Abdulhannan [11] | 2008 | 3 | F | Yes | Yes | Yes | 2 weeks GCV, recovered |
12 | Ramos-Boluda [12] | 2009 | 2 | M | Yes | Yes | Yes | 2 weeks GCV, recovered |
13 | Nigroi* [13] | 2009 | 3 | M | N/A | Yes | Yes | 8 weeks OGCV, recovered |
14 | Nigro*[13] | 2009 | 2 | M | N/A | No | Yes | 8 weeks OGCV, recovered |
15 | Nigro*[13] | 2009 | 3 | F | N/A | No | Yes | 8 weeks OGCV, recovered |
16 | Gupta [14] | 2010 | 1 | NA | No | NA | Yes | 6 weeks GCV, recovered |
17 | Rogalidou [15] | 2010 | 3 | M | No | Yes | No | Recovered without GCV therapy |
18 | Tzialla [16] | 2010 | 21d | F | Yes | No | Yes | Colonic Stricture, recovered with GCV × 6 weeks |
19 | Refai [17] | 2012 | 2 | F | Yes | No | No | Died |
20 | Louazon [18] | 2014 | 2 | M | Yes | Yes | No | Recovered without GCV therapy |
21 | Novakova [19] | 2014 | 2 | M | Yes | Yes | Yes | Colonic Stenosis |
22 | Sue | 2015 | 2 | M | Yes | No | Yes | 4 weeks GCV + 4 weeks VGC, recovered |
23 | Sue | 2015 | 10 | M | No | No | No | Recovered without GCV therapy |
Totals | --- | --- | 2 | M (76%) | 72% | 45% | 61% | Complications (22%) |
*Infants reported by Nigro in a case series; although 2 M / 1F were reported, gender was not specifically assigned to specific cases. Weights between 3.34–3.4kg were reported but not assigned, and age at admission was designated at 2 – 3 months but also not specifically assigned.