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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Pediatr Infect Dis J. 2016 May;35(5):573–576. doi: 10.1097/INF.0000000000001080

Table 1.

Reported cases of invasive CMV enterocolitisin immunocompetent infants. GCV, ganciclovir; VGCV, valganciclovir; TPN, total parenteral nutrition.

Case Author Year Age
(m)
Gender Breast
Fed
Bloody
Stool
Ganciclovir Outcome /
Complications
1 Huang [1] 1996 1.5 F No No No Ileal perforation
2 Jonkhoff [2] 1997 1.5 M No Yes No Recovered without therapy
3 Quiros-Tejeira [3] 1999 2 M Yes No Yes 2 weeks GCV, Recovered
4 Fox [4] 1999 1 M Yes Yes Yes 4 weeks GCV, recovered.
5 Shinawi [5] 2001 14 M No NA No Recovered without GCV therapy
6 Iwanaga [6] 2003 2 F Yes No Yes 2 weeks GCV, Recovered
7 Rongkavilit [7] 2004 2 M Yes No Yes 3 weeks GCV, Recovered
8 Hinds [8] 2004 2 M Yes Yes No 3 weeks TPN, Recovered without GCV
9 Shimizu [9] 2005 12 M Yes No No Prolonged TPN with pancreatitis and pseudocyst. Recovered without GCV
10 Buonomo [10] 2006 7 M Yes Yes Yes 5 weeks VGC, Recovered
11 Abdulhannan [11] 2008 3 F Yes Yes Yes 2 weeks GCV, recovered
12 Ramos-Boluda [12] 2009 2 M Yes Yes Yes 2 weeks GCV, recovered
13 Nigroi* [13] 2009 3 M N/A Yes Yes 8 weeks OGCV, recovered
14 Nigro*[13] 2009 2 M N/A No Yes 8 weeks OGCV, recovered
15 Nigro*[13] 2009 3 F N/A No Yes 8 weeks OGCV, recovered
16 Gupta [14] 2010 1 NA No NA Yes 6 weeks GCV, recovered
17 Rogalidou [15] 2010 3 M No Yes No Recovered without GCV therapy
18 Tzialla [16] 2010 21d F Yes No Yes Colonic Stricture, recovered with GCV × 6 weeks
19 Refai [17] 2012 2 F Yes No No Died
20 Louazon [18] 2014 2 M Yes Yes No Recovered without GCV therapy
21 Novakova [19] 2014 2 M Yes Yes Yes Colonic Stenosis
22 Sue 2015 2 M Yes No Yes 4 weeks GCV + 4 weeks VGC, recovered
23 Sue 2015 10 M No No No Recovered without GCV therapy
Totals --- --- 2 M (76%) 72% 45% 61% Complications (22%)
i

*Infants reported by Nigro in a case series; although 2 M / 1F were reported, gender was not specifically assigned to specific cases. Weights between 3.34–3.4kg were reported but not assigned, and age at admission was designated at 2 – 3 months but also not specifically assigned.