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. 2016 Mar 20;7(6):656–663. doi: 10.7150/jca.13674

Figure 3.

Figure 3

Effects of miR-874 on tumor cell proliferation and invasion. (A) MTS assays were performed at days 1, 2 and 3 after transfection of HLE cells with miR-874 mimic (transfection of 36 h is defined as day 0). (B) MTS assays were performed at days 1, 2 and 3 after transfection of A375 cells with miR-874 mimic (transfection of 36 h is defined as day 0). (C) Apoptosis profiles for A375 cells transfected with miR-874 mimic or miR-NC staining for Annexin V/PI. The quantitative analysis is shown in the right panel. (D) Apoptosis profiles for A375 cells transfected with miR-874 mimic or miR-NC staining for JC-1. The quantitative analysis is shown in the right panel. (E) Transwell invasion analysis of A375 cells treated with miR-874 mimic or miR-NC. The quantitative analysis is shown in the right panel. (F) Transwell invasion analysis of HLE cells treated with miR-874 mimic or miR-NC. (G) Transwell invasion analysis of HLE cells treated with miR-874 inhibitor or inhibitor-NC. (mean ± S.D.; * p < 0.05; ** p < 0.01; *** p < 0.001).