Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 13;7:30. doi: 10.3389/fendo.2016.00030

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Choe, Huh, Hwang, Kim and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Actin cytoskeleton and insulin-stimulated GLUT4 translocation control in adipocytes. In adipocytes, cytosolic and cortical actin organization is involved in GLUT4 storing vesicle (GSV) transport by insulin stimulation. When adipocytes are hypertrophied, enlarged unilocular lipid droplets and expanded cell volume may impede cortical actin dynamics, resulting in improper/deficient translocation of GSVs. This indicates the importance of the adipocyte cytoskeleton in the regulation of adipocyte glucose metabolism in response to insulin.