Table 6.

Association of VNTR genotypes in XRCC5 promoter with familial breast cancer-affected and -unaffected groups.

Genotype	Control	Affected case	Odds ratio	95% CI	P-value	Adjusted	Unaffected case	Odds ratio	95% CI	P-value	Adjusted
BRCA1+
2R/2R	100	45	1.94	1.26–2.95	0.0016	0.0096	16	2.09	1.05–3.97	0.0221	0.1326
2R/1R	255	87	1.58	1.11–2.26	0.0087	0.0388	26	1.25	0.69–2.23	0.3190	0.4785
1R/1R	190	32	0.55	0.35–0.84	0.0049	0.0196	13	0.69	0.33–1.35	0.2906	0.4978
1R/0R	38	0	0	0–0.29	0.0001	0.0012	1	0.28	0.01–1.73	0.2414	0.5794
BRCA2+
2R/2R	100	17	1.75	0.97–3.15	0.0865	0.1038	10	2.82	1.13–6.58	0.0174	0.2088
2R/1R	255	39	1.94	1.14–3.32	0.0101	0.0242	12	1.05	0.45–2.38	1	1
1R/1R	190	13	0.54	0.27–1.04	0.0680	0.0907	4	0.37	0.09–1.11	0.0632	0.1896
1R/0R	38	0	0	0–0.73	0.0427	0.0641	2	1.16	0.13–4.93	0.6916	0.7545
BRCAx
2R/2R	100	20	1.55	0.90–2.67	0.1101	1	3	2.01	0.52–7.69	0.3945	0.5257
2R/1R	255	41	1.27	0.84–1.82	0.2882	0.3096	6	1.79	0.54–5.92	0.3654	0.5481
1R/1R	190	18	0.59	0.35–1.02	0.0583	0.3168	1	0.23	0.03–1.84	0.1885	0.5655
1R/0R	38	7	1.34	0.58–3.10	0.4913	1	0	0	0–4.75	1	1