. 2016 Mar 30;2016:5045248. doi: 10.1155/2016/5045248

Table 1.

pDCs in SLE.

Markers used to identify subset	Reference	Frequency	Phenotype	Function
BDCA2⁺ CD123⁺	Tucci et al. [82]	↓ in blood, correlated with LN and ↑ in kidney (more than other DC subsets)

BDCA2⁺ (blood) and BDCA4⁺ (kidney)	Fiore et al. [78]	↓ in blood in active disease and ↑ in kidney (more than other DC subsets)	DCs in kidney were immature (DC-LAMP⁻), localized to tubulointerstitium, in clusters, and lacked dendrites

BDCA2⁺ Lin.⁻ HLA-DR⁺	Migita et al. [77]	↓ in blood

CD123^high CD11c⁻ CD16⁻ HLA-DR⁺	Henriques et al. [80]	↓ in blood in active disease

BDCA2⁺CD123^high	Kwok et al. [90]	Normal in blood	↓ IFNα production by PBMC per pDC upon CpG stimulation

BDCA2⁺ BDCA4⁺ CD123⁺	Jin et al. [79]	↑ in blood per total PBMC	Normal HLA-DR, CD86, CD83, CCR7	↑ T cell proliferation in MLR

BDCA2⁺ CD11c⁻	Gerl et al. [81]	na	Normal HLA-DR, CD86, CD83, CCR7, CD40, BAFF, CCR1, and CCR5 and ↓ CMKLR1	↑ basal and CCL19-specific migration

BDCA-2⁺ CD4⁺ CD11c⁻ Lin⁻	Hagberg and Rönnblom [86]		↓ SLAMF5/CD84, SLAMF7/CRACC/CD319, normal SLAMF1, SLAMF2/CD48, SLAMF3/CD229, SLAMF4/CD244, and SLAMF6/CD352