Table 2. Results of the hierarchical regression analysis for the influence of cell source, passage number and donor on doubling time of matched FP- and SF-MSCs.
| Factor | Fixed/Random effect | Coefficient or SD (days) | p-value |
|---|---|---|---|
| Cell source (SF) | Fixed | 8.3 (6.1–10.4) | <0.001 |
| Passage number | Fixed | 1.4 (0.8–2.0) | <0.001 |
| Passage by donor | Random | 0.54 (0.19–1.1) | 0.004 |
Note: Coefficients and standard deviation (SD) based on a linear mixed effect model. P-values are from Wald tests (fixed effects) and likelihood ratio tests (random effects).