Table 2.
Association between history of infertility and mammographic density
| Age adjusted | Fully adjustedb | ||
|---|---|---|---|
| N | MD (95 % CI) | MD (95 % CI) | |
| Absolute dense volume, cm3 | |||
| No infertility | 34,360 | 0.00 (Reference) | 0.00 (Reference) |
| History of infertilitya | 8953 | 3.12 (2.22 to 4.02) | 1.53 (0.70 to 2.35) |
| Absolute non-dense volume, cm3 | |||
| No infertility | 34,360 | 0.0 (Reference) | 0.0 (Reference) |
| History of infertilitya | 8953 | 13.8 (4.9 to 22.8) | 7.6 (1.8 to 13.4) |
| Percent dense volume, pp | |||
| No infertility | 34,360 | 0.00 (Reference) | 0.00 (Reference) |
| History of infertilitya | 8953 | 0.19 (0.04 to 0.35) | 0.09 (−0.06 to 0.23) |
Abbreviations: BMI body mass index, CI confidence interval, MD mean difference (difference in mean density between exposed group and reference group), pp percentage points
aAll women who reported ever trying to conceive for at least 1 year without success
bAdjusted for age at mammography, BMI, age at menarche, cigarette smoking, alcohol consumption, education level, family history of breast cancer, parity and menopausal status