Table 2.
Vibriocidal antibody responses of study participants by pregnancy status
| Infecting strain | Antibody | Pregnant (n=14) | Non-pregnant (n=130) | p-value | ||
|---|---|---|---|---|---|---|
| n | Median (IQR) | n | Median (IQR) | |||
|
| ||||||
| Vibriocidal (* Study Days) | ||||||
| Overall | Day 2 | 14 | 80 (10 – 640) | 128 | 80 (20 – 160) | 0.84 |
| Day 7 | 14 | 2560 (1280 – 8960) | 122 | 5120 (2560 – 10240) | 0.32 | |
| Day 21 | 11 | 2560 (640 – 5120) | 120 | 2560 (1280 – 5120) | 0.66 | |
| V.cholerae O1 | Day 2 | 10 | 480 (50 – 640) | 105 | 80 (40 – 320) | 0.19 |
| Day 7 | 10 | 3840 (2560,17920) | 99 | 5120 (2560 – 10240) | 0.97 | |
| Day 21 | 9 | 5120 (1280,5120) | 97 | 5120 (1280 – 5120) | 0.95 | |
| V. cholerae O139 | Day 2 | 4 | 8 (5 – 28) | 23 | 20 (10 – 80) | 0.27 |
| Day 7 | 4 | 640 (520 – 800) | 23 | 1280 (640 – 2560) | 0.10 | |
| Day 21 | 2 | 163 (84 – 241) | 23 | 640 (640 – 1280) | 0.05 | |
*
Patients presenting to the icddr,b Dhaka hospital with acute watery diarrhea (study day 1); Antibody titers, from patients at baseline on study day 2 and again at follow-up visits on study days 7 and 21.