Table 3.

Responses to LPS of study participants by pregnancy status

Infecting strain	Antibody (* Study Days)	Pregnant (n=14)		Non-pregnant (n=130)		p-value
		n	Median (IQR)	n	Median (IQR)
Overall	LPS IgA
	Day 2	14	22 (18 – 31)	130	22 (12 – 39)	0.95
	Day 7	14	103 (32 – 250)	124	151 (73 – 268)	0.26
	Day 21	11	81(30 – 177)	120	97 (49 – 184)	0.49
	LPS IgG
	Day 2	14	72 (47 – 122)	130	79 (55 – 106)	0.87
	Day 7	14	180 (98 – 248)	124	227 (164 – 292)	0.12
	Day 21	11	258 (106 – 283)	120	238 (150 – 313)	0.30
V.cholerae O1	LPS IgA
	Day 2	10	24 (19 – 31)	107	21 (11 – 37)	0.49
	Day 7	10	169 (87 – 308)	101	162 (74 – 293)	0.97
	Day 21	9	106 (30 – 184)	97	89 (43 – 200)	0.80
	LPS IgG
	Day 2	10	99 (60 – 138)	107	75 (55 – 103)	0.30
	Day 7	10	224 (158 – 259)	101	226 (163 – 297)	0.73
	Day 21	9	268 (123 – 298)	97	230 (146 – 318)	0.91
V. cholerae O139	LPS IgA
	Day 2	4	21 (14 – 26)	23	30 (14 – 42.67)	0.25
	Day 7	4	38 (21 – 54.17)	23	102 (64 – 170)	0.02
	Day 21	2	47 (38 – 55.33)	23	117 (68 – 158)	0.09
	LPS IgG
	Day 2	4	53 (37 – 64)	23	90 (72 – 111)	0.02
	Day 7	4	107 (81 – 130)	23	228 (195 – 277)	0.01
	Day 21	2	83 (75 – 91)	23	246 (219 – 300)	0.03

^*Patients presenting to the icddr,b Dhaka hospital with acute watery diarrhea (study day 1); Antibody titers, from patients at baseline on study day 2 and again at follow-up visits on study days 7 and 21.