Table 4.

Responses to CtxB of study participants by pregnancy status

Infecting strain	Antibody (* Study Days)	Pregnant (n=14)		Non-pregnant (n=130)		p-value
		n	Median (IQR)	n	Median (IQR)
Overall	CtxB IgA
	Day 2	14	19 (16 – 38)	130	22 (12 – 44)	0.75
	Day 7	14	92 (58 – 160)	124	123 (65 – 204)	0.49
	Day 21	11	56 (48 – 115)	120	71 (41 – 125)	0.89
	CtxB IgG
	Day 2	14	109 (75 – 131)	130	98 (61 – 157)	0.87
	Day 7	14	288 (213 – 352)	124	260 (194 – 425)	0.98
	Day 21	11	369 (252 – 401)	120	285 (213 – 399)	0.40
V.cholerae O1	CtxB IgA
	Day 2	10	20 (16 – 60)	107	22 (12 – 41)	0.75
	Day 7	10	92 (64 – 156)	101	111 (57 – 175)	0.96
	Day 21	9	68 (48 – 135)	97	67 (36 – 100)	0.44
	CtxB IgG
	Day 2	10	117 (85 – 131)	107	99 (63 – 160)	0.70
	Day 7	10	288 (266 – 347)	101	260 (191 – 411)	0.52
	Day 21	9	378 (281 – 411)	97	286 (202 – 410)	0.13
V. cholerae O139	CtxB IgA
	Day 2	4	19 (16 – 20)	23	25 (15 – 49)	0.19
	Day 7	4	97 (52 – 151)	23	191 (129 – 304)	0.08
	Day 21	2	50 (49 – 51)	23	107 (74 – 176)	0.04
	CtxB IgG
	Day 2	4	92 (63 – 119)	23	75 (53 – 132)	1.00
	Day 7	4	231 (124 – 327)	23	260 (219 – 430)	0.25
	Day 21	2	180 (151 – 209)	23	282 (234 – 385)	0.11

^*Patients presenting to the icddr,b Dhaka hospital with acute watery diarrhea (study day 1); Antibody titers, from patients at baseline on study day 2 and again at follow-up visits on study days 7 and 21.