Figure 1.

Bisdemethoxycurcumin (BDMC) inhibited transforming growth factor-β1 (TGF-β1)-induced epithelial-to-mesenchymal transition. (a) Phase contrast images of 95D cells untreated or treated with TGF-β1 (5 ng/mL), BDMC (5 μmol/L) or both after 48 h; (b) The protein expression of E-cadherin, vimentin, fibronectin, and Snail in 95D cells treated or not treated with TGF-β1 and BDMC together, GAPDH was a loading control; (c) The expression of E-cadherin and vimentin as detected by immunofluorescence in 95D cells untreated or treated with TGF-β1, BDMC or both. Blue signal represented DAPI nuclei staining, and green signal represented vimentin or E-cadherin expression (original magnification × 100).