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. 2015 May 20;128(10):1376–1383. doi: 10.4103/0366-6999.156795

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Copyright: © 2015 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Wnt inhibitory factor-1 (WIF-1) ablation inhibited bisdemethoxycurcumin (BDMC) effect on transforming growth factor-β1 (TGF-β1)-induced epithelial-to-mesenchymal transition (EMT). (a) WIF-1 small interfering-RNA (siRNA) significantly inhibited its protein expression in 95D cells; (b) The 95D cells with no siRNA, control siRNA, and WIF-1 siRNA were treated with TGF-β1 and BDMC and analyzed for EMT marker proteins, E-cadherin, vimentin, fibronectin, and Snail. GAPDH was a loading control.