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Chemosensitivity and bystander effect in vitro. (a and b) Tumor growth curve and survival analysis of nude mice inoculated with cytosine deaminase (CD) and/or human sulfatase-1 (Hsulf-1) gene therapy with 5-fluorocytosine treatment; (c and d) *P < 0.05 compared with HepG2/blank; †P < 0.05 compared with HepG2/Hsulf-1 or HepG2/blank; ‡P < 0.05 compared with HepG2/CD, HepG2/Hsulf-1 or HepG2/blank.
