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. Author manuscript; available in PMC: 2016 Jul 14.
Published in final edited form as: Nature. 2015 Dec 14;529(7585):221–225. doi: 10.1038/nature16161

Extended Data Figure 7. Il25 is expressed only in tuft cells during worm infection and H. polygyrus infection also induces tuft cell hyperplasia.

Extended Data Figure 7

a, b, Jejunum of Il25F25/F25 (a) and wild-type control (b) mice infected for 7 days with N. brasiliensis stained by immunohistochemistry for RFP (red), indicated lineage markers (green), and DAPI (blue). c, Jejunum of indicated mice left untreated or infected 14 days with H. polygyrus and stained by immunohistochemistry for DAPI (blue), EPCAM (green) and DCLK1 (red). Scale bars, 50 μm. d.p.i., days post-H. polygyrus infection. Images are representative of one (c) or two (a, b) independent experiments. In a, b, n =2; in c, n = 1 (uninfected) or n =2 (infected).