Table I.

Baseline demographics: Clinical characteristics of pregnant women with ADPKD vs. simple cyst

Characteristics	ADPKD n=54	Simple Cyst n=92	P
Total number of pregnancies	146	265
Number of pregnancies per patient	2.7±2.4	2.9±1.4	.04*
one pregnancy	17 (31.5)	13 (14.1)	.04†
two pregnancies	15 (27.8)	32 (34.8)
≥ three pregnancies	22 (40.7)	47 (51.1)
Race
Caucasian	52 (96.3)	92 (100)	.14#
African American	1 (1.9)	0 (0)
Asian	1 (1.9)	0 (0)
Age by 12/31/2010	45.2±12.6	49.3±11.4	.09
Maternal age at live birth
First live birth	27.9±6.3	26.9±5.1	.46
Second live birth	29.0±5.0	29.5±4.6	.84
Third or more live births	32.0±5.1	32.7±4.9	.77
Family history	25 (46.3)	0 (0)	<.001
Paternal lineage	12 (22.2)	0 (0)
Maternal lineage	13 (24.1)	0 (0)
Age at diagnosis	28.9±8.6	29.3±8.4	.77
Before first pregnancy	25 (46.3)	50 (54.3)
During first pregnancy	12 (22.2)	20 (21.7)
After first pregnancy	17 (31.5)	22 (24.0)
Spectrum disorders	31 (57.4)	7 (7.6)	<.001
Hepatic cysts	24 (44.4)	1 (1.1)	<.001
Ovarian cysts	5 (9.3)	5 (5.4)	.50
Splenic cysts	1 (1.9)	1 (1.1)	.47
Thyroid cysts	1 (1.9)	0 (0)	.37

Abbreviation: ADPKD = autosomal dominant polycystic kidney disease.

Data are n (%) or mean ± standard deviation unless otherwise specified.

^*Wilcoxon rank test.

^†χ2 test.

^#Fisher exact test.