Table 2. Mixed model analysis between the WBV and CON groups at baseline, three- and six month assessments.
Data are mean (SEM).
| WBV | CON | Mixed models analysis (p value) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Outcomes | Variables | Assessment 1 (Baseline) | Assessment 2 (3 months) | Assessment 3 (6 months) | Assessment 1 (Baseline) | Assessment 2 (3 months) | Assessment 3 (6 months) | Group | Time | Group*time |
| Functional Ability | mHAQ (max. of 3) | 1.22(0.19) | 1.02(0.19) | 0.92(0.19)* | 1.13(0.20) | 1.06(0.20) | 1.17(0.20) | 0.79 | 0.25 | 0.18 |
| HRQoL and Disease activity | Fatigue (/5) | 4.4(0.63) | 1.1(0.65)* | 3.7(0.67) | 3.4(0.67) | 3.7(0.75) | 3.7(0.72) | 0.40 | 0.04 | 0.01 |
| Pain (/5) | 3.90(0.69) | 3.07(0.71) | 4.75(0.71) | 4.00(0.71) | 4.83(0.71) | 4.75(0.78) | 0.40 | 0.34 | 0.26 | |
| CDAI | 11.10(1.88) | 9.59(1.88) | 9.64(1.94) | 8.20(1.94) | 10.33(1.94) | 8.80(1.94) | 0.59 | 0.91 | 0.56 | |
| Physical activity | Average AC (/day) | 7296(828) | 7424(864) | 7194(884) | 6984(855) | 6613(855) | 6385(971) | 0.53 | 0.85 | 0.88 |
| Sedentary (%/day) | 68(2.6) | 68(2.8) | 70(2.8) | 69(2.7) | 70(2.8) | 71(3.2) | 0.67 | 0.57 | 0.96 | |
| Light(%/day) | 21(1.70) | 21(1.80) | 19(1.85) | 20(1.75) | 20(1.75) | 20(2.08) | 0.80 | 0.65 | 0.92 | |
| Moderate (%/day) | 11(1.27) | 11(1.32) | 10(1.35) | 11(1.31) | 10(1.31) | 9(1.47) | 0.59 | 0.50 | 0.91 | |
| Vigorous (%/day) | 0.02(0.01) | 0.02(0.01) | 0.01(0.01) | 0.01(0.01) | 0.01(0.01) | 0.00(0.01) | 0.31 | 0.75 | 0.91 | |
| Breaks sedentary time (#/day) | 61(3.3) | 63(3.5) | 63(3.6) | 67(3.4) | 60(3.4)* | 61(4.0) | 0.90 | 0.59 | 0.14 | |
| Activity bouts (#/day) | 3.1(0.59) | 3.4(0.60) | 3.0(0.61) | 2.8(0.61) | 2.1(0.61)* | 1.8(0.64)* | 0.26 | 0.14 | 0.16 | |
| Bone | Hip BMD (g.cm2) | 1.01(0.05) | 0.96(0.05) | 0.94(0.05) | 0.97(0.05) | 0.94(0.05) | 0.84(0.05)* | 0.37 | 0.01 | 0.50 |
| Spine BMD (g.cm2) | 0.92(0.04) | 0.92(0.04) | 0.92(0.04) | 0.91(0.04) | 0.91(0.04) | 0.91(0.04) | 0.87 | 0.84 | 0.74 | |
| Whole Body BMD (g.cm2) | 1.09(0.03) | 1.10(0.03)^ | 1.10(0.03)* | 1.07(0.03) | 1.07(0.03) | 1.05(0.03)* | 0.47 | 0.15 | <0.01 | |
| Body Composition | BMI (kg/m2) | 34(2.1) | 34(2.1) | 33(2.1)* | 34(2.2) | 34(2.2) | 34(2.2) | 0.84 | 0.58 | 0.05 |
| Fat mass (kg) | 37(3) | 36(3) | 35(3)* | 31(3) | 32(3) | 35(3)* | 0.43 | 0.44 | <0.01 | |
| Lean mass (kg) | 46(2) | 46(2) | 45(2) | 42(2) | 42(2) | 40(2)* | 0.13 | <0.01 | <0.01 | |
| SMI | 7.8(0.39) | 8.0(0.39)^ | 8.0(0.39)^ | 7.7(0.40) | 7.9(0.40)* | 7.4(0.41)* | 0.64 | 0.02 | <0.01 | |
Breaks in sedentary time are adjusted for % total sedentary time at each time point.
mHAQ–modified health assessment questionnaire, HRQoL–health related quality of life, CDAI–clinical disease activity index, AC–activity counts, BMD–bone mineral density, BMI—body mass index, SMI–skeletal mass index.
* Main effects significantly different from baseline after posthoc analysis (p<0.05).
^ Main effects showed trend towards significant difference from baseline after posthoc analysis (p<0.07).