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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Int Forum Allergy Rhinol. 2015 Nov 12;6(1):25–33. doi: 10.1002/alr.21666

FIGURE 1.

FIGURE 1

(A) Pre-Op and Post-Op (6 months) quality of life assessment of patients undergoing functional endoscopic sinus surgery as a function of polyp status and TAS2R38 genotype. Patients were classified based on the presence or absence of nasal polyps and subsequently genotyped for the TAS2R38. Patients were divided into PAV/PAV or non–PAV/PAV diplotype (AVI/AVI, PAV/AVI or rare haplotypes). (B) Pre-Op and Post-Op (6 months) quality of life assessment of patients undergoing functional endoscopic sinus surgery as a function of polyp status and TAS2R38 genotype. Surgical outcomes as measured by the change in quality of life (SNOT-22: pre-post). In nonpolypoid patients TAS2R38 genotype significantly correlates with favorable vs suboptimal outcomes (**p < 0.01). AVI = nonfunctional receptor haplotype containing alanine, valine and isoleucine; ns = not significant; PAV = functional receptor haplotype containing proline, alanine, and valine; Post-Op = postoperative; Pre-Op = preoperative; SNOT-22 = 22-item Sino-Nasal Outcome Test.