. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Int Forum Allergy Rhinol. 2015 Nov 12;6(1):25–33. doi: 10.1002/alr.21666

TABLE 2.

Mean change between preoperative and postoperative (6-month) SNOT-22 scores^*

	All patients (n = 123)			Polyp patients (n = 82)			Nonpolypoid patients (n = 41)
	n	Mean ± SD change	p	n	Mean ± SD change	p	n	Mean ± SD change	p
All patients	123	25 ± 23		82	30 ± 21	0.002	41	16 ± 24	0.002
Genotype
Non-PAV	96	24 ± 22	0.13	62	30 ± 20	0.85	34	12 ± 22	0.006
PAV/PAV	27	31 ± 25		20	29 ± 26		7	38 ± 21
Taste sensitivity^a
PTC <5.5	41	25 ± 24	0.53	29	33 ± 19	0.80	12	4 ± 21	0.03
PTC ≥5.5	54	28 ± 23		34	31 ± 24		20	21 ± 20
Denatonium <4	34	27 ± 25	0.97	28	31 ± 23	0.76	6	5 ± 22	0.20
Denatonium ≥4	62	26 ± 22		36	33 ± 21		26	17 ± 21
Quinine <3	42	28 ± 25	0.45	29	34 ± 24	0.68	13	16 ± 23	0.89
Quinine ≥3	54	25 ± 22		35	31 ± 20		19	14 ± 21
Sucrose <6	43	25 ± 24	0.46	30	29 ± 23	0.27	13	14 ± 25	0.86
Sucrose ≥6	53	28 ± 22		34	35 ± 20		19	16 ± 20
Other variables
Female gender	50	24 ± 24	0.6	26	34 ± 23	0.20	12.9	19.9 ± 13	0.272
Male gender	73	26 ± 22		56	28 ± 20		21.2	28 ± 21
White	111	24 ± 23	0.09	71	29 ± 22	0.25	16.0	24 ± 16
Non-white	12	36 ± 20		11	37 ± 21
Age less than 50 years	45	30 ± 21	0.07	35	33 ± 21	0.22	20.1	20 ± 20	0.566
Age 50 years or greater	78	22 ± 24		47	27 ± 22		15.1	25 ± 15
Never smoked	76	24 ± 20	0.35	54	28 ± 18	0.33	13.5	22.0 ± 14	0.368
Current or former smoker	43	28 ± 26		26	34 ± 27		20.2	24 ± 20
Asthma	72	27 ± 20	0.39	58	29 ± 19	0.60	17.9	21 ± 18	0.757
No asthma	51	23 ± 27		24	32 ± 27		15.5	25 ± 16
ASA	18	35 ± 20	0.06	18	35 ± 20	0.28	16.3
No ASA	105	23.6 ± 23		64	28 ± 22
Diabetes	15	26 ± 18	0.79	10	31 ± 18	0.89	19.0	17 ± 19	0.790
No diabetes	108	25 ± 24		72	30 ± 22		15.9	25 ± 16
No AFS	98	25 ± 23	0.91	58	31 ± 22	0.60
AFS	25	26 ± 23		24	28 ± 21
Primary surgery	32	22 ± 25	0.42	17	24 ± 25	0.18	21.3	26 ± 21	0.314
Revision surgery	91	26 ± 22		65	31 ± 20		13.5	22 ± 14	</TB>

Values of p show whether each variable affects the difference between the preoperative and postoperative 6-month SNOT-22 scores.

For each taste sensitivity test, patients were categorized as having a taste intensity above or below the median score for the overall population (5.5, 4, 3, and 6, respectively, for PTC, denatonium, quinine, and sucrose).

AFS = allergic fungal sinusitis; ASA = acetylsalicylic acid; PAV = functional receptor haplotype containing proline, alanine, and valine; PTC = phenylthiocarbamide; SD = standard deviation; SNOT = Sino-Nasal Outcome Test.