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. 2016 Mar 31;2016:4639654. doi: 10.1155/2016/4639654

Figure 1.

Figure 1

The mRNA expressions of calpain 2, CaN, and NFATs in left atrial tissues isolated from patients with AF and SR. In comparison with SR subjects, significantly increased mRNA levels of calpain 2 (128.37 ± 63.01% versus 100 ± 36.07%, P = 0.015), CnA α (154.90 ± 100.38% versus 100 ± 98.44%, P = 0.020), CnA β (159.16 ± 144.34% versus 100 ± 73.36%, P = 0.037), and NFAT-c3 (130.79 ± 100.00% versus 100 ± 85.48%, P = 0.028), but not NFAT-c4 (119.40 ± 85.51% versus 100 ± 89.82%, P = 0.340), were observed in patients with AF. ∗ P < 0.05 versus SR. AF indicates atrial fibrillation; CnA alpha and CnA beta indicate α and β isoforms of catalytic A subunit in calcineurin; NFAT indicates nuclear factor of activated T cells; SR indicates sinus rhythm.