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Immunohistochemical localization of calpain 2 in atrial cardiomyocytes ((a) AF group, ×200; (b) SR group, ×400). Calpain 2, brown-stained granules, was localized in the cytoplasm of atrial myocytes, but not in endocardium or epicardium. Enhanced expression of calpain 2 was observed in samples from patients with AF compared to those from SR group. AF indicates atrial fibrillation; SR indicates sinus rhythm.
