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. 2015 Aug 21;57:225–238. doi: 10.1007/s13353-015-0309-2

Fig. 1.

Fig. 1

Subsequent stages of bacterial biofilm formation/dispersal and their genetic regulation. (i) reversible, followed by irreversible, attachment to the surface, (ii) formation of microcolonies, (iii and iv) biofilm maturation leading to the formation of bacterial consortia, and (v) biofilm dispersal. The regulatory involvement of quorum sensing (QS), bis-(3’-5’)-cyclic diguanosine monophosphate (c-di-GMP), and small RNAs (sRNAs) is shown by the arrows