Fig. 2.

Domain structures of RPA subunits and MEIOB. a Schematic representation of MEIOB and RPA subunits protein domains. The folded domains and unfolded linkers are presented as boxes and lines respectively. The red and blue boxes represent MEIOB and RPA subunit OB- folds, respectively. The orange domains illustrate zinc ion-binding domains. The grey boxes represent domains that are not involved in ssDNA-binding activity, such as the N-terminal domain of RPA1 and the phosphorylation domain (PD) and the winged-helix domain (WHD) of RPA2. b Stereo ribbon presentation of predicted MEIOB structure model obtained from the RaptorX server (Kallberg et al. 2012) and visualized with Jmol (www.jmol.org). OB-folds 1, 2, and 3 and zinc ion-binding domain are represented in red, green, yellow, and orange, respectively. Unfolded linkers are represented in grey