Table 2.
Summary of laboratory tests over time since index date, in RA and non-RA patients
| Blood test | At index date |
1 year after index |
3 years after index |
5 years after index |
||||
|---|---|---|---|---|---|---|---|---|
| n (%) | Mean (s.d.) | n (%) | Mean (s.d.) | n (%) | Mean (s.d.) | n (%) | Mean (s.d.) | |
| RA patients (n = 24 859) | ||||||||
| HDL-C, mmol/l | 5709 (23.0) | 1.4 (0.5) | 5378 (21.6) | 1.4 (0.5) | 4474 (18.0) | 1.5 (0.5) | 3688 (14.8) | 1.5 (0.5) |
| LDL-C, mmol/l | 4621 (18.6) | 3.0 (1.0) | 4386 (17.6) | 3.0 (1.0) | 3597 (14.5) | 3.0 (1.0) | 3030 (12.2) | 2.9 (1.0) |
| Total cholesterol, mmol/l | 8018 (32.3) | 5.2 (1.2) | 7485 (30.1) | 5.2 (1.2) | 6025 (24.2) | 5.1 (1.1) | 4815 (19.4) | 5.1 (1.1) |
| Triglyceride level, mmol/l | 5847 (23.5) | 1.6 (1.0) | 5458 (22.0) | 1.6 (1.0) | 4437 (17.8) | 1.6 (1.0) | 3661 (14.7) | 1.6 (0.9) |
| Diastolic BP, mmHg | 17 779 (71.5) | 79.0 (10.1) | 16 021 (64.4) | 79.0 (10.0) | 12 173 (49.0) | 79.0 (10.0) | 9157 (36.8) | 78.5 (10.0) |
| Systolic BP, mmHg | 17 779 (71.5) | 136.2 (19.2) | 16 021 (64.4) | 136.5 (18.9) | 12 173 (49.0) | 136.5 (18.9) | 9157 (36.8) | 136.3 (18.1) |
| CRP, mg/l | 8434 (33.9) | 24.6 (34.9) | 8607 (34.6) | 18.8 (29.8) | 4967 (20.0) | 18.8 (29.8) | 3647 (14.7) | 14.8 (25.9) |
| ESR, mm/h | 11 694 (47.0) | 31.9 (26.0) | 11 440 (46.0) | 27.0 (23.5) | 6912 (27.8) | 27.0 (23.5) | 5165 (20.8) | 23.9 (20.9) |
| HbA1c, % | 1448 (5.8) | 7.1 (1.5) | 1475 (5.9) | 6.9 (1.5) | 1222 (4.9) | 6.9 (1.5) | 1009 (4.1) | 7.0 (1.6) |
| FG, mmol/l | 1645 (6.6) | 5.5 (1.5) | 1515 (6.1) | 5.5 (1.7) | 1215 (4.9) | 5.5 (1.7) | 1029 (4.1) | 5.4 (1.4) |
| Non-RA patients (n = 87 304) | ||||||||
| HDL-C, mmol/l | 19 754 (22.6) | 1.4 (0.5) | 18 791 (21.5) | 1.4 (0.5) | 16 092 (18.4) | 1.5 (0.5) | 13 113 (15.0) | 1.5 (0.5) |
| LDL-C, mmol/l | 16 340 (18.7) | 3.0 (1.0) | 15 558 (17.8) | 3.0 (1.0) | 13 282 (15.2) | 2.9 (1.1) | 10 953 (12.5) | 2.9 (1.0) |
| Total cholesterol, mmol/l | 27 177 (31.1) | 5.2 (1.2) | 25 524 (29.2) | 5.2 (1.2) | 21 041 (24.1) | 5.1 (1.2) | 16 786 (19.2) | 5.1 (1.2) |
| Triglyceride level, mmol/l | 20 462 (23.4) | 1.6 (1.0) | 19 361 (22.2) | 1.6 (1.0) | 16 251 (18.6) | 1.6 (0.9) | 13 123 (15) | 1.6 (0.9) |
| Diastolic BP, mmHg | 60 889 (69.7) | 79.3 (10.7) | 54 339 (62.2) | 78.9 (10.1) | 40 515 (46.4) | 78.9 (10.1) | 30 049 (34.4) | 78.5 (9.7) |
| Systolic BP, mmHg | 60 889 (69.7) | 136.4 (19.6) | 54 339 (62.2) | 136.4 (58.9) | 40 515 (46.4) | 136.4 (58.9) | 30 049 (34.4) | 136.4 (17.7) |
| CRP, mg/l | 5095 (5.8) | 10.6 (24.6) | 4915 (5.6) | 10.8 (25.7) | 4229 (4.8) | 10.8 (25.7) | 3482 (4) | 10.7 (25.9) |
| ESR, mm/h | 10 630 (12.2) | 17.2 (19.1) | 9986 (11.4) | 16.8 (17.2) | 7876 (9.0) | 16.8 (17.2) | 6382 (7.3) | 17.2 (17.0) |
| HbA1c, % | 5365 (6.1) | 7.2 (1.5) | 5116 (5.9) | 7.2 (1.6) | 4264 (4.9) | 7.2 (1.5) | 3479 (4.0) | 7.1 (1.5) |
| FG, mmol/l | 5730 (6.6) | 5.7 (1.8) | 5529 (6.3) | 5.7 (1.7) | 4751 (5.4) | 5.7 (1.6) | 3967 (4.5) | 5.6 (1.6) |
BP: blood pressure; FG: fasting blood glucose; HbA1c: haemoglobin A1c; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.