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. 2016 Apr 14;6:24413. doi: 10.1038/srep24413

Figure 2. Skeletal abnormalities of the heterozygous FBN1 mutant cloned pigs.

Figure 2

(A,E) Appearance of the thorax of a WT pig (A) and an FBN1 mutant pig with pectus excavatum (E, red arrowhead). (B–D,F–H) Multidetector CT imaging of the skeletal structures of a WT piglet (B–D) and an FBN1 mutant piglet (#6, F–H). The WT and FBN1 mutant piglets had a barrel-shaped (B) and a conically shaped (G) thorax, respectively. Delayed mineralization of the primary spongiosa and epiphyseal nucleus (arrowhead) was recognized in the humerus (G), the os coxa (H), the femur (H), and the fibula (H) of the FBN1 mutant piglet.