Table 2. Univariate analysis of outcome predictors.
DFS |
OS |
|||||||
---|---|---|---|---|---|---|---|---|
Stage/Gene | Mutant Number | P | Hazard Ratio | 95% CI | P | Hazard Ratio | 95% CI | |
KRAS | ||||||||
Stage II | 28 | 0.389 | 2.749 | 0.249 to 30.324 | 0.400 | 2.802 | 0.254 to 30.911 | |
Stage III | 25 | 0.412 | 0.574 | 0.152 to 2.163 | 0.404 | 0.568 | 0.151 to 2.144 | |
Stage II and III | 53 | 0.727 | 0.824 | 0.276 to 2.458 | 0.692 | 0.802 | 0.269 to 2.393 | |
BRAF | ||||||||
Stage II | 6* | – | – | – | – | – | – | |
Stage III | 4 | 0.578 | 1.792 | 0.229 to 14.030 | 0.563 | 1.833 | 0.234 to 14.336 | |
Stage II and III | 10 | 0.958 | 0.946 | 0.124 to 7.235 | 0.986 | 0.982 | 0.128 to 7.510 | |
PIK3CA | ||||||||
Stage II | 8* | – | – | – | – | – | – | |
Stage III | 11 | 0.945 | 1.056 | 0.228 to 4.891 | 0.904 | 1.099 | 0.237 to 5.086 | |
Stage II and III | 19 | 0.920 | 0.926 | 0.207 to 4.140 | 0.961 | 0.964 | 0.216 to 4.306 |
*No death events in this group.