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. 2016 Apr 7;14(2):1559325816640682. doi: 10.1177/1559325816640682

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Effect of estrogen or bisphenol A (BPA) on gene expression of histone-modifying enzymes (HMEs) in OVCAR3 cells. A, OVCAR3 cells were treated with the indicated doses of estrogen for 24 hours, and the expression of SET8 (left panel) or SIRT1 (right panel) was analyzed. B, OVCAR3 cells were treated with the indicated doses of BPA for 24 hours, and the expression of SET8 (left panel) or SIRT1 (right panel) was analyzed. ImageJ was used to quantitate the results, and the expression of each gene was normalized to GAPDH from the same sample. Results are from 3 independent experiments (*P < .05).