Figure 2. Global cognition score over time by APOE ε4 allele and levels of occupational cognitive requirements.

(A) APOE ε4+: Participants with an APOE ε4 allele. (B) APOE ε4−: Participants without an APOE ε4 allele. The predicted values are derived from linear mixed models adjusted for race, sex, income decile, education, education-squared, age, age-squared, education × time, income × time, and age × time.