History of dieting and sucrose exposure model |
12-h food deprivation is followed by 12-h access to sucrose solution79,80. |
After few days, subjects escalate sucrose intake during the first hour of access. |
History of dieting and stress model |
Repetition of cycles of food-restriction and refeeding. At the end of each cycle, subjects are exposed to a stressor81–86. |
After three restriction/refeeding stress cycles, stressed subjects escalate their palatable food intake. |
The limited access model |
Subjects are never food deprived. They are given sporadic, time limited access to either vegetable fat87,88 or sucrose diet17,19,37,89–91. |
Subjects with sporadic access to palatable food escalate their intake. |