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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: CNS Spectr. 2015 Oct 26;20(6):537–545. doi: 10.1017/S1092852915000668

Table 1.

Summary of the most predictive binge eating preclinical models, divided into three major classes, as a function of the procedures used to induce binge eating in the animal.

Features Binge-eating episodes
History of dieting and sucrose exposure model 12-h food deprivation is followed by 12-h access to sucrose solution79,80. After few days, subjects escalate sucrose intake during the first hour of access.
History of dieting and stress model Repetition of cycles of food-restriction and refeeding. At the end of each cycle, subjects are exposed to a stressor8186. After three restriction/refeeding stress cycles, stressed subjects escalate their palatable food intake.
The limited access model Subjects are never food deprived. They are given sporadic, time limited access to either vegetable fat87,88 or sucrose diet17,19,37,8991. Subjects with sporadic access to palatable food escalate their intake.