Table 3.
Cumulative incidence of doctor diagnosed asthma by phenotype and birth weight, by sex and race
| NBW (n=293) Birth Weight >2500 grams % (CI), n* |
MLBW (n=251) Birth Weight 2000–2500 grams % (CI), n* |
LLBW (n=136) Birth Weight <2000 grams % (CI), n* |
Overall P value For Weight | P value for trend | |
|---|---|---|---|---|---|
| TOTAL | |||||
| Early Onset Transient | 2.4 (1.0, 4.9), 7 | 2.4 (0.9, 5.1), 6 | 2.2 (0.5, 6.3), 3 | 0.992 | 0.919 |
| Early Onset Persistent | 5.2 (2.9, 8.3), 15 | 5.2 (2.8, 8.7), 13 | 8.8 (4.6, 14.9), 12 | 0.265 | 0.181 |
| Child Onset Remittent | 3.1 (1.4, 5.8), 9 | 1.6 (0.4, 4.0), 4 | 1.5 (0.2, 5.2), 2 | 0.408 | 0.224 |
| Child Onset Persistent | 2.0 (0.7, 4.4), 6 | 2.8 (1.1, 5.7), 7 | 4.4 (1.6, 9.4), 6 | 0.385 | 0.179 |
| Late Child Onset Remittent | 1.7 (0.5, 3.9), 5 | 0.4 (0.0, 2.2), 1 | 2.2 (0.5, 6.3), 3 | 0.249 | 0.973 |
| Late Child Onset Persistent | 3.4 (1.6, 6.2), 10 | 6.8 (4.0, 10.6), 17 | 8.1 (4.1, 14.0), 11 | 0.086 | 0.032 |
| MALES (n=320) | |||||
| Early Onset Transient | 2.8 (0.7, 6.9), 4 | 2.9 (0.6, 8.1), 3 | 4.3 (0.9, 12.0), 3 | 0.818 | 0.583 |
| Early Onset Persistent | 3.4 (1.1, 7.9), 5 | 5.7 (2.1, 12.0), 6 | 8.6 (3.2, 17.7), 6 | 0.285 | 0.114 |
| Child Onset Remittent | 3.4 (1.1, 7.9), 5 | 1.9 (0.2, 6.7), 2 | 1.4 (0.0, 7.7), 1 | 0.601 | 0.333 |
| Child Onset Persistent | 3.4 (1.1, 7.9), 5 | 1.9 (0.2, 6.7), 2 | 7.1 (2.4, 15.9), 5 | 0.196 | 0.292 |
| Late Child Onset Remittent | 2.8 (0.7, 6.9), 4 | 0.0 (0.0, 3.5), 0 | 1.4 (0.0. 7.7), 1 | 0.221 | 0.294 |
| Late Child Onset Persistent | 2.1 (0.4, 5.9), 3 | 9.5 (4.7, 16.8), 10 | 7.1 (2.4, 15.9), 5 | 0.034 | 0.055 |
| FEMALES (n=360) | |||||
| Early Onset Transient | 2.0 (0.4, 5.8), 3 | 2.1 (0.4, 5.9), 3 | 0.0 (0.0, 5.4), 0 | 0.504 | 0.361 |
| Early Onset Persistent | 6.8 (3.3, 12.1), 10 | 4.8 (1.9, 9.6), 7 | 9.1 (3.4, 18.6), 6 | 0.482 | 0.717 |
| Child Onset Remittent | 2.7 (0.7, 6.8), 4 | 1.4 (0.2, 4.9), 2 | 1.5 (0.0, 8.2), 1 | 0.683 | 0.466 |
| Child Onset Persistent | 0.7 (0.0, 3.7), 1 | 3.4 (1.1, 7.8), 5 | 1.5 (0.0, 8.2), 1 | 0.224 | 0.409 |
| Late Child Onset Remittent | 0.7 (0.0, 3.7), 1 | 0.7 (0.0, 3.8), 1 | 3.0 (0.4, 10.5), 2 | 0.258 | 0.196 |
| Late Child Onset Persistent | 4.7 (1.9, 9.5), 7 | 4.8 (1.9, 9.6), 7 | 9.1 (3.4, 18.8), 6 | 0.382 | 0.267 |
| BLACKS (n=302) | |||||
| Early Onset Transient | 3.5 (0.9, 8.7), 4 | 3.5 (0.9, 8.7), 4 | 1.4 (0.0, 7.5), 1 | 0.661 | 0.452 |
| Early Onset Persistent | 4.3 (1.4, 9.9), 5 | 9.6 (4.9, 11.5), 11 | 8.3 (3.1, 17.3), 6 | 0.291 | 0.237 |
| Child Onset Remittent | 4.3 (1.4, 9.9), 5 | 2.6 (0.5, 7.4), 3 | 1.4 (0.0, 7.5), 1 | 0.489 | 0.235 |
| Child Onset Persistent | 2.6 (0.5, 7.4), 3 | 5.2 (1.9, 11.0), 6 | 1.4 (0.0, 7.5), 1 | 0.315 | 0.811 |
| Late Child Onset Remittent | 1.7 (0.2, 6.1), 2 | 0.0 (0.0, 3.2), 0 | 2.8 (0.3, 9.7), 2 | 0.240 | 0.711 |
| Late Child Onset Persistent | 1.7 (0.2, 6.1), 2 | 4.3 (1.4, 9.9 ), 5 | 5.6 (1.5, 13.6), 4 | 0.350 | 0.157 |
| WHITES (n=378) | |||||
| Early Onset Transient | 1.7 (0.3, 4.9), 3 | 1.5 (0.2, 5.2), 2 | 3.1 (0.4, 10.8), 2 | 0.702 | 0.567 |
| Early Onset Persistent | 5.6 (2.7, 10.1), 10 | 1.5 (0.2, 5.2), 2 | 9.4 (3.5, 19.3), 6 | 0.038 | 0.642 |
| Child Onset Remittent | 2.2 (0.6, 5.7), 4 | 0.7 (0.0, 4.0), 1 | 1.6 (0.0, 8.4), 1 | 0.569 | 0.509 |
| Child Onset Persistent | 1.7 (0.3, 4.9), 3 | 0.7 (0.0, 4.0), 1 | 7.8 (2.6, 17.3), 5 | 0.007 | 0.032 |
| Late Child Onset Remittent | 1.7 (0.3, 4.9), 3 | 0.7 (0.0, 4.0), 1 | 1.6 (0.0, 8.4), 1 | 0.753 | 0.765 |
| Late Child Onset Persistent | 4.5 (2.0, 8.7), 8 | 8.8 (4.6, 14.9), 12 | 10.9 (4.5, 21.2), 7 | 0.146 | 0.054 |
*
n= number of asthma cases