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. 2016 Apr 14;16:50. doi: 10.1186/s12890-016-0216-2

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© Jiang et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Differential levels of miR-21 and miR-26a in plasma from wheezing children. a RT-qPCR results of candidate miRNAs in plasma from 20 LRI control and 20 wheezing + LRI children. b RT-qPCR results of miR-21, miR-25, miR-26a, miR-133a and miR-148 in plasma from 35 indifferent control, 35 LRI control and 70 wheezing + LRI children. c Scattered dot plots of plasma miR-21 and miR-26a in wheezing + LRI children of different ages and genders. Cel-miR-39 was used as internal control for circulating miRNA. Differences among three groups were analyzed by Kruskal-Wallis test followed Mann-Whitney test for difference between groups according to data characteristics. **: p < 0.01, ***: p < 0.001