Table 1.
T. dermatis strains tested | MIC (mg/liter) | Method | Reference | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amphotericin Ba | Flucytosine | Fluconazole | Itraconazole | Voriconazole | Posaconazole | Caspofungin | ||||||||||
GM | Range | GM | Range | GM | Range | GM | Range | GM | Range | GM | Range | GM | Range | |||
1 | 0.25 | >64 | >256 | >16 | >16 | >8 | >16 | Sensititreb | Our study | |||||||
8 | 0.24 | 0.015-16.0 | 58.6 | 16.0-128.0 | 12.3 | 1.0-128.0 | 0.58 | 0.06-8.0 | 0.48 | 0.06-16.0 | ND | ND | Eucast | Rodriguez-Tudela et al 2005 [7] | ||
1 | 0.5 | 8 | 0.06 | 0.06 | ND | 16 | CLSI | Chagas-Neto et al 2009 [2] | ||||||||
1 | 0.13 | ND | 2 | 0.06 | 0.06 | 0.015 | ND | Eucast | Taverna et al. 2014 [16] |
GM geometrical mean, MIC minimal inhibitory concentration, ND not done
aEffectiveness of amphotericin B is limited in Trichosporon infections [12]
bSusceptibility was tested using a commercial microdilution test (Yeast Sensititre OneTM) by the national reference center (Radboud University Medical Center, Nijmegen, The Netherlands)