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. 2016 Apr 14;16:148. doi: 10.1186/s12879-016-1477-3

Table 1.

MICs of various antifungal agents against 11 clinical Trichosporon dermatis isolates

T. dermatis strains tested MIC (mg/liter) Method Reference
Amphotericin Ba Flucytosine Fluconazole Itraconazole Voriconazole Posaconazole Caspofungin
GM Range GM Range GM Range GM Range GM Range GM Range GM Range
1 0.25 >64 >256 >16 >16 >8 >16 Sensititreb Our study
8 0.24 0.015-16.0 58.6 16.0-128.0 12.3 1.0-128.0 0.58 0.06-8.0 0.48 0.06-16.0 ND ND Eucast Rodriguez-Tudela et al 2005 [7]
1 0.5 8 0.06 0.06 ND 16 CLSI Chagas-Neto et al 2009 [2]
1 0.13 ND 2 0.06 0.06 0.015 ND Eucast Taverna et al. 2014 [16]

GM geometrical mean, MIC minimal inhibitory concentration, ND not done

aEffectiveness of amphotericin B is limited in Trichosporon infections [12]

bSusceptibility was tested using a commercial microdilution test (Yeast Sensititre OneTM) by the national reference center (Radboud University Medical Center, Nijmegen, The Netherlands)