Table 1.
Extracts/treatments | Dose (mg/kg) | PCV | Body weight | ||
---|---|---|---|---|---|
D0 | D-4 | D0 | D-4 | ||
NC | 0 | 52.80 ± 0.48 | 40.58 ± 0.64b | 27.90 ± 0.64 | 23.98 ± 1.46 |
dH2O | 200 | 53.59 ± 2.88 | 44.75 ± 0. 96a | 27.76 ± 0.20 | 26.88 ± 0.25a |
400 | 55.09 ± 1.01 | 47.49 ± 2.22a | 28.12 ± 0.13 | 29.56 ± 0.32a | |
600 | 51.98 ± 0.99 | 50.38 ± 0.52a | 26.88 ± 0.15 | 27.20 ± 0.55a | |
CH3OH | 200 | 54.66 ± 1.15 | 42.67 ± 0.67b | 26.50 ± 1.41 | 26.29 ± 2.53a |
400 | 51.69 ± 1.11 | 40.13 ± 1.84b | 27.56 ± 1.41 | 26.22 ± 1.40a | |
600 | 53.98 ± 0.99 | 56.09 ± 0.44b | 29.10 ± 2.58 | 30.09 ± 2.16a | |
CHCl3 | 200 | 56.94 ± 0.50 | 46.36 ± 0.6b | 29.38 ± 2.39 | 24.36 ± 1.44b |
400 | 54.14 ± 1.56 | 42.30 ± 0.87b | 33.70 ± 8.76 | 28.23 ± 6.90b | |
600 | 51.68 ± 0.74 | 43.23 ± 0.66b | 28.66 ± 2.55 | 25.00 ± 0.51b | |
CQ | 25 | 54.73 ± 0.27 | 53.37 ± 0.21a | 28.80 ± 0.23 | 30.97 ± 0.92b |
Key: Values are presented as mean ± SEM; n = 5; PCV packed cell volume, NC negative control (3 % tween 80), dH2O distilled water, CH 3 OH methanol, CHCl 3 chloroform, CQ chloroquine (positive control); a = the difference between day 0 and day 4 is not significant (P > 0.05); b = the difference between day 0 and day 4 is significant (P < 0.05)