Table 3.

Mixed-effects regression model to estimate the changes in parasitaemia in 16 patients with severe malaria

Parameter	Coefficient	95 % confidence interval	p value
Log initial parasitaemia/µLa	12.02	11.24; 12.79	<0.0001
RBC exchangeb	2.47	1.43; 3.51	<0.0001
Parasite elimination rate (/h)c	−0.13	−0.15; −0.10	<0.0001

RBC red blood cell

^aLog initial parasitaemia for individuals who did not receive RBC exchange (intercept of the regression model)

^bDifference in log initial parasitaemia for individuals who received RBC exchange vs those who did not

^cDifference in log parasitaemia per unit increase of time (hour)