. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: Acad Radiol. 2016 Feb 18;23(4):496–506. doi: 10.1016/j.acra.2015.12.020

Table 1.

Guidelines for Choosing Values for Claim Statements

Step	Description
1	Choose statistical metric for performance
2	Determine patient and/or tumor characteristics that can degrade performance for the quantitative imaging biomarker
3	Identify plausible set of values for performance
4	Consider clinical requirements for performance
5	Consider the sample size requirements for actors to test their imaging procedure against the claim value
6	Choose the performance value from the plausible set of values in step 3, taking into consideration steps 4–5.