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Sweat Cl– concentration is a measure of CFTR function in humans. (A) Role of the CFTR anion channel in Cl– reabsorption by sweat ducts. (B) Finger sweat Cl– test. Correlation between age and sweat Cl– concentration in healthy subjects (n = 73, p < 0.01). Closed circles: males; open circles: females. Adapted from references 80 and 84.
