Table 1.
Clinical background characteristics of patients infected and not infected with extended-spectrum β-lactamase (ESBL)-producing E. coli
| Variable | ESBL (+) n=14 (%) |
ESBL (–) n=14 (%) |
P | |
|---|---|---|---|---|
| Demographics | ||||
| Age (year): mean ± SD | 72.1 ± 11.1 | 67.2 ± 16.7 | *N.S. | |
| Gender: Number of males | 8 (57.1) | 8 (57.1) | N.S. | |
| BMI (mean ± SD) | 20.0 ± 3.7 | 19.9 ± 3.6 | *N.S. | |
| Comorbidities | ||||
| Respiratory disease | 3 (21.4) | 3 (21.4) | N.S. | |
| Cardiovascular disease | 3 (21.4) | 2 (14.3) | N.S. | |
| Hypertension | 6 (42.9) | 7 (50.0) | N.S. | |
| Diabetes mellitus | 5 (35.7) | 6 (42.9) | N.S. | |
| Renal disease | 3 (21.4) | 2 (14.3) | N.S. | |
| Liver disease | 0 (0) | 0 (0) | N.S. | |
| Malignant disease | 9 (64.3) | 8 (57.1) | N.S. | |
| Use of corticosteroids | 2 (14.3) | 4 (28.6) | N.S. | |
| Hospital admission ward | ||||
| ICU | 3 (21.4) | 3 (21.4) | N.S. | |
| Medical | 8 (57.1) | 6 (42.9) | N.S. | |
| Surgical | 3 (21.4) | 5 (35.7) | N.S. | |
| Previous hospitalization within 3 months | 3 (21.4) | 5 (35.7) | N.S. | |
| Type of invasive device | ||||
| Urethral catheter | 4 (28.6) | 5 (35.7) | N.S. | |
| Tracheal tube | 2 (14.3) | 2 (14.3) | N.S. | |
| Central venous catheter | 8 (57.1) | 5 (35.7) | N.S. | |
| Other | 2 (14.3) | 3 (21.4) | N.S. | |
| Infected regions | ||||
| Urine samples | 6 (42.9) | 5 (35.7) | N.S. | |
| Respiratory samples | 2 (14.3) | 1 (7.1) | N.S. | |
| Blood samples | 1 (7.1) | 2 (14.3) | N.S. | |
| Stool samples | 2 (14.3) | 0 (0) | N.S. | |
| Other samples | 3 (21.4) | 5 (35.7) | N.S. | |
| Days until detection of ESBL producer during hospitalization (mean ± SD) | 36.4 ± 35.3 | 21.7 ± 12.5 | *N.S. | |
| Previous isolates | ||||
| Pseudomonas aeruginosa | 3 (21.4) | 3 (21.4) | N.S. | |
| MRSA | 2 (14.3) | 1 (7.1) | N.S. | |
| Candida | 2 (14.3) | 2 (14.3) | N.S. | |
ESBL (+): patients infected with ESBL-producing E. coli; ESBL (–): patients not infected with ESBL-producing E. coli; N.S.: not significant; BMI: body mass index; ICU: intensive care unit; MRSA: methicillin-resistant Staphylococcus aureus. Renal disease was defined as having a serum creatinine level >2 mg/dL. All statistical tests were performed using Fisher’s exact test except for data indicated by *, for which Mann-Whitney U-test was used.