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Association between genetic polymorphisms ABCG2 34G>A and toxicity
| GG | GA+AA | P value | |
|---|---|---|---|
| Skin rash | |||
| Grade 2≦ (N = 23) | 10 | 13 | P = 0.046 |
| Grade 1≧ (N = 60) | 41 | 19 | |
| Diarrhea | |||
| Grade 2≦ (N = 4) | 2 | 2 | P = 0.638 |
| Grade 1≧ (N = 79) | 49 | 30 | |
| Liver injury | |||
| Grade 2≦ (N = 15) | 10 | 5 | P = 0.773 |
| Grade 1≧ (N = 68) | 41 | 27 | |
| Interstitial lung disease (ILD) | |||
| Grade 1≦ (N = 5) | 4 | 1 | P = 0.644 |
| Grade 0 (N = 78) | 47 | 31 |
