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Association between genetic polymorphisms ABCG2 421C>A and toxicity
| CC | CA+AA | P value | |
|---|---|---|---|
| Skin rash | |||
| Grade 2≦ (N = 23) | 14 | 9 | P = 0.473 |
| Grade 1≧ (N = 60) | 31 | 29 | |
| Diarrhea | |||
| Grade 2≦ (N = 4) | 3 | 1 | P = 0.621 |
| Grade 1≧ (N = 79) | 42 | 37 | |
| Liver injury | |||
| Grade 2≦ (N = 15) | 8 | 7 | P = 1 |
| Grade 1≧ (N = 68) | 37 | 31 | |
| Interstitial lung disease (ILD) | |||
| Grade 1≦ (N = 5) | 4 | 1 | P = 0.369 |
| Grade 0 (N = 78) | 41 | 37 |
