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Association between genetic polymorphisms ABCB1 3435C>T and toxicity
| CC | CT+TT | P value | |
|---|---|---|---|
| Skin rash | |||
| Grade 2≦ (N = 23) | 7 | 16 | P = 0.787 |
| Grade 1≧ (N = 60) | 16 | 44 | |
| Diarrhea | |||
| Grade 2≦ (N = 4) | 1 | 3 | P = 1 |
| Grade 1≧ (N = 79) | 22 | 57 | |
| Liver injury | |||
| Grade 2≦ (N = 15) | 3 | 12 | P = 0.542 |
| Grade 1≧ (N = 68) | 20 | 48 | |
| Interstitial lung disease (ILD) | |||
| Grade 1≦ (N = 5) | 3 | 2 | P = 0.127 |
| Grade 0 (N = 78) | 20 | 58 |
