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. 2016 Jan 28;5(4):617–622. doi: 10.1002/cam4.622

Table 2.

Magnitude of HR changes

	Total population (n = 1053)	Postbaseline HR
	Total population (n = 1053)	<60 bpm (n = 441)	≥60 bpm (n = 612)
Magnitude of HR change, bpm
Mean baseline pretreatment HR (SD)	88.3 (16.1)	82.2 (14.2)^a	92.6 (15.9)^a
Median baseline pretreatment HR (range)	86.0 (43.0–145.0)	80.0 (43.0–143.0)	91.0 (54.0–145.0)
Mean decrease in HR from baseline (SD)	25.0 (15.8)	30.0 (13.8)^a	21.4 (16.1)^a
Median decrease in HR from baseline (range)	24.0 (−27.0–85.0)	28.0 (1.0–85.0)	20.0 (−27.0–67.0)
Time to HR change, weeks
Mean time to the lowest HR recorded (SD)	15.4 (14.1)	20.2 (15.5)^a	12.0 (11.8)^a
Median time to the lowest HR recorded (range)	9.6 (0.7–75.4)	15.1 (1.7–71.1)	7.7 (0.7–75.4)
Mean time to within 5 bpm of the lowest HR recorded (SD)	11.0 (10.4)	14.2 (11.3)^a	8.8 (9.0)^a
Median time to within 5 bpm of the lowest HR recorded (range)	6.4 (0.7–72.1)	9.4 (1.7–63.1)	6.1 (0.7–72.1)

bpm, beats per minute; HR, heart rate; SD, standard deviation.

^a

P<0.0001 (t‐test for comparison of means).