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. 2016 Feb 2;5(4):684–692. doi: 10.1002/cam4.623

Figure 1.

Figure 1

miR‐708 has a positive correlation with breast cancer cells growth and invasion. (A). Transfection efficiency was confirmed at 48 h by using RT‐PCR. *P < 0.05.(B). Overexpression of miR‐708 apparently inhibited MDA‐MB‐231 cells invasion, whereas inhibition of miR‐708 obviously promoted its invasion. **P < 0.01, ***P < 0.001. (C). Morphology of MDA‐MB‐231 cells at 48 h after plating the same number cells in the dish (left: transfected with pre‐miR‐control, right: transfected with pre‐miR‐708). (D). CCK‐8 assay was performed to measure the growth rate of MDA‐MB‐231 cells upon pre‐miR‐708. (E). Inhibition of miR‐708 promoted MDA‐MB‐231 cells invasion **P < 0.01. (F). Inhibition of miR‐708 promoted MDA‐MB‐231 cells proliferation. *P < 0.05. (G). Morphology of MDA‐MB‐231 cells at 48 h after plating the same number cells in the dish (left: transfected with Inhibitor control, right: transfected with miR‐708‐inhibitor). *P < 0.05.