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The effects of geniposide (GE; 50 mg kg−1 for 7 weeks) were abolished after knock‐down of GLP‐1 receptor in the heart. (A–B) Summary data of HW/BW and HW/TL (n = 12). (C) The cross‐sectional areas of myocytes (n = 6). (D) Histology results from cross‐sections of hearts with haematoxylin and eosin staining. (E) Echocardiographic parameters in the heart after knock down GLP‐1R (n = 10). (F) Expression levels of the transcripts of ANP and β‐MHC (n = 6). * P < 0.05.
