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. 2016 Mar 1;20(5):825–835. doi: 10.1111/jcmm.12808

Figure 7.

Figure 7

Regulation of cell motility by S100A4‐RAGE interaction. Relative scratch widths of wild type A375, A375‐hS100A4, and A375‐hRAGE cells either (A) untreated, treated with BFA, S100A4‐siRNA, and blocking Anti‐RAGE antibody, or (B) treated with fivefold molar excess (150 ng/ml) of sRAGE, fivefold (150 ng/ml; in A375 cells) or 100‐fold molar excess (3000 ng/ml) of S100A4 (in A375‐hRAGE cells) are shown. Initial scratch width was set as 100% (mean ± S.E.M., n ≥ 3, *P < 0.05, versus untreated; § P < 0.05, versus untreated A375 cells; # P < 0.05 versus untreated A375‐hS100A4 cells).