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. 2016 Jan 19;20(5):939–948. doi: 10.1111/jcmm.12782

Figure 5.

Figure 5

MiR‐17~92 targets Pten and p21. (A) Prediction of the binding sites of miR‐17~92 on the 3′UTRs of the Pten and p21 genes using the Targetscan online website. (B) Schematic representations of the 3′UTRs of the Pten and p21 genes and their WT miR‐17~92 (red) and mutant binding sites (blue triangle), which were cloned downstream from a luciferase reporter (Luc). (C) Specific repression of the Luc‐Pten and p21 3′UTR reporters with miR‐17~92 mimics. The mimic miR‐1 was used as a control, *P < 0.05.