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. 2016 Jan 19;20(5):939–948. doi: 10.1111/jcmm.12782

Figure 6.

Figure 6

MiR‐17~92 promotes cell proliferation by inhibiting p21 and Pten expression in the regenerating liver. (A) Immunoblotting of cyclin D1, Pten, and p21 in regenerating livers of male and female mice. Histone H3 was used as a loading control. (B) The relative fold changes of cyclin D1, Pten and p21 in CKO and WT mice. The data represent the mean ± S.D.; n = 3; *P < 0.05. (C and D) Immunoblotting of p‐Akt was substantially reduced in the regenerating livers of the female CKO mice, especially at 24 and 36 hrs after 70% PH. The data represent the mean ± S.D.; n = 3; *P < 0.05.