Table 3.
Clinicopathological features of PAX5 methylation in non‐small cell lung cancer
| Clinicopathological features | Number (n = 47) | PAX5 methylation status | P‐value | |
|---|---|---|---|---|
| Methylated | Unmethylated | |||
| Age (year) | ||||
| >60 | 28 | 21 | 7 | 0.518 |
| ≤60 | 19 | 12 | 7 | |
| Gender | ||||
| Male | 31 | 21 | 10 | 0.742 |
| Female | 16 | 12 | 4 | |
| Smoking status | ||||
| Yes | 28 | 18 | 10 | 0.344 |
| No | 19 | 15 | 4 | |
| Histology | ||||
| Squamous carcinoma | 22 | 10 | 12 | 0.006 |
| Adenocarcinoma | 19 | 18 | 1 | |
| Lung adenosquamous carcinoma | 5 | 4 | 1 | |
| Large cell carcinoma | 1 | 1 | 0 | |
| Differentiation | ||||
| Moderately/Well | 19 | 10 | 9 | 0.055 |
| Poorly | 10 | 7 | 3 | |
| Unknown | 18 | 16 | 2 | |
| TNM stage | ||||
| I | 22 | 13 | 9 | 0.395 |
| II | 9 | 8 | 1 | |
| III | 12 | 9 | 3 | |
| IV | 4 | 3 | 1 | |
| Lymph node metastasis | ||||
| Yes | 21 | 16 | 5 | 0.528 |
| No | 26 | 17 | 9 | |
| Distant metastasis | ||||
| Yes | 4 | 3 | 1 | 1 |
| No | 43 | 30 | 13 | |