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. 2016 Jan 22;20(5):874–890. doi: 10.1111/jcmm.12772

Figure 8.

Figure 8

The potential molecular mechanisms underlying the promotion of hADSC viability and neural differentiation potential effects induced by maxadilan. (A) Domain structure analysis of maxadilan using PredictProtein. (B) The 3D structures of PACAP and maxadilan using SWISSMODEL. (C) Assessment of protein expression levels of β‐catenin, Cyclin D1, c‐myc and survivin in different groups using Western blot assays. (D) Detection of the Bcl‐2 levels in different groups using ELISA. (E) Comparison of the Caspase 3 activity in different groups using Caspase 3 activity assays. (F) Assessment of protein expression levels of NSE, Nestin, NF‐M and Tuj‐III in different groups using Western blot assays. (G) Quantification of the cAMP levels in different groups using ELISA. (H) Diagram of the potential molecular mechanisms underlying the promotion of hADSC viability and neural differentiation potential effects induced by maxadilan. Differences with *P < 0.05 were considered significant. Differences with # P > 0.05 were considered not significant.